ABSTRACT

This book presents the multifaceted aspects of rare earth elements (REEs), focusing on both their potential benefits and adverse health effects. The adverse impacts of REEs on human and environmental health raise a growing concern not only in the scientific community but also among a number of stakeholders, potentially including students, media workers, and decision makers. The recognized and potential benefits arising from REE-related technological applications may envisage their further advantages.

A limited number of books have been devoted so far to REEs, and they mainly focus on REE-related chemistry, mineralogy, economy, and developing technologies for these elements. This book presents recent research achievements in REE-associated health effects, which have been mostly confined to journal reports on individual laboratory studies so far. It is an updated and balanced approach to REE research and technology. It provides novel yet established information as stated in the title "At the Crossroads between Toxicity and Safety," with particular emphasis on the hormesis phenomenon.

Trends in Occupational Toxicology of Rare Earth Elements. Levels and Biodistribution of Rare Earths in Human Tissues. Rare Earth Elements, Oxidative Stress and Disease. Cerium Oxide Nanoparticles-associated Oxidant and Antioxidant Effects and Mechanism. Rare Earth Elements and Plants. Rare Earth Elements and Microorganisms. Rare Earth Element Toxicity to Marine and Freshwater Algae. Exposure to Rare Earth Elements in Animals: a Systematic Review of Biological Effects in Mammals, Fish and Invertebrates. Hazard Assessment and the Evaluation of Rare Earth Element Dose-Response Relationships. Rare earth elements as phosphate binders: From kidneys to lakes. Rare Earth Elements: Modulation of Calcium-Driven Processes in Epithelium and Stroma. Rare Earth Elements Equilibria in Aqueous Media. Conclusions and Research Priorities.