ABSTRACT

Focusing on the roles of different segments of DNA, Statistics in Human Genetics and Molecular Biology provides a basic understanding of problems arising in the analysis of genetics and genomics. It presents statistical applications in genetic mapping, DNA/protein sequence alignment, and analyses of gene expression data from microarray experiments.

chapter 2|22 pages

Basics of Likelihood Based Statistics

chapter 3|16 pages

Markers and Physical Mapping

chapter 4|20 pages

Basic Linkage Analysis

chapter 7|14 pages

Sequence Alignment

chapter 9|12 pages

Hidden Markov Models

chapter 10|14 pages

Feature Recognition in Biopolymers

chapter 12|14 pages

Statistical Genomics

chapter 13|20 pages

Detecting Differential Expression

chapter 14|18 pages

Cluster Analysis in Genomics

chapter 15|18 pages

Classification in Genomics