ABSTRACT

Design Principles and Analysis Techniques for HRQoL Clinical TrialsSAS, R, and SPSS examples realistically show how to implement methods Focusing on longitudinal studies, Design and Analysis of Quality of Life Studies in Clinical Trials, Second Edition addresses design and analysis aspects in enough detail so that readers can apply statistical meth

chapter 1|28 pages

Introduction and Examples

chapter 2|24 pages

Study Design and Protocol Development

chapter 3|30 pages

Models for Longitudinal Studies I

chapter 4|22 pages

Models for Longitudinal Studies II

chapter 5|20 pages

Moderation and Mediation

chapter 6|24 pages

Characterization of Missing Data

chapter 7|14 pages

Analysis of Studies with Missing Data

chapter 8|18 pages

Simple Imputation

chapter 9|28 pages

Multiple Imputation

chapter 10|30 pages

Pattern Mixture and Other Mixture Models

chapter 11|28 pages

Random Effects Dependent Dropout

chapter 12|8 pages

Selection Models

chapter 13|20 pages

Chaper 13: Multiple Endpoints

chapter 14|28 pages

Composite Endpoints and Summary Measures

chapter 16|20 pages

Analysis Plans and Reporting Results