ABSTRACT

Macromolecules in the body form noncovalent associations, such as DNA-protein or protein-protein complexes, that control and regulate numerous cellular functions. Understanding how changes in the concentration and conformation of these macromolecules can trigger physiological responses is essential for researchers developing drug therapies to treat

chapter 1|46 pages

Binding Sites

chapter 2|32 pages

Binding Isotherms

chapter 4|48 pages

Cooperativity

chapter 5|34 pages

Binding to Lattices of Sites

chapter 6|30 pages

Choosing a Method and Analyzing the Data