ABSTRACT
This reference examines innovations in separation science for improved sensitivity and cost-efficiency, increased speed, higher sample throughput and lower solvent consumption in the assessment, evaluation, and validation of emerging drug compounds. It investigates breakthroughs in sample pretreatment, HPLC, mass spectrometry, capillary electrophor
Preface, Contributors, l. Sample Pretreatment in Clinical Chemistry, 2. Separation Science in Therapeutic Drug Monitoring, 3. The Impact of Chirality in Pharmacokinetics and Therapeutic Drug Monitoring, 4. HPLC in Bioavailability Examination, 5. Validation of HPLC Analyses in Therapeutic Drug, 6. Analysis of Illicit Drugs with Chromatographic Methods, 7. Biogenic Amine Neurotransmitters: Their Importance and Measurement in Human Tissue and Body Fluids, 8. Clinical Applications of Affinity Chromatography, 9. Immunoaffinity Chromatography in Clinical Analysis, 10. Electrospray Tandem Mass Spectrometry in the Biochemical Genetics Laboratory, 11. Application of Thin-Layer Chromatography in Clinical Chemistry, 12. Applications of Capillary Electrophoresis in Clinical Analysis of Drugs, Index
