ABSTRACT
In recent years, the emphasis in drug development has been the design of new delivery systems rather than new drugs. It is the aim of innovative pharmaceutical scientists to design the new dosage forms to overcome the body's barrier mechanisms which have specifically evolved to exclude foreign material.
This book provides an integrated appro
TABLE OF CONTENTS
chapter 1|1 pages
Cell Membranes, Epithelial Barriers and Drug Absorption
INTRODUCTIONTHE PLASMA MEMBRANE The phospholipid bilayer Dynamic behaviour of membranes
chapter 2|1 pages
Parenteral Drug Delivery
INTRAVENOUS DELIVERY Physiology Advantages and disadvantages of intravenous delivery
chapter 3|1 pages
Drug Delivery to the Oral Cavity or Mouth
ANATOMY AND PHYSIOLOGY The oral cavity The palate
chapter 4|1 pages
Oesophageal Transit
INTRODUCTIONAN ATOMY AND PHYSIOLOGY Oesophagus Gastro-oesophageal junction or cardia
chapter 6|1 pages
Drug Absorption from the Small Intestine ANATOMY AND PHYSIOLOGY OF THE SMALL INTESTINE
ANATOMY AND PHYSIOLOGY OF THE SMALL INTESTINE Gross morphology Mucosa Organisation of the mucosa
chapter 7|1 pages
Drug Delivery to the Large Intestine and Rectum
ANATOMY AND PHYSIOLOGY OF THE COLON Interspecies differences in structure
chapter 9|1 pages
Nasal Drug Delivery
ANATOMY AND PHYSIOLOGY Nasal epithelia Nasal lymphatic system Nasal secretion
chapter 10|1 pages
Pulmonary Drug Delivery
STRUCTURE AND FUNCTION OF THE PULMONARY SYSTEM The lung Upper airway Structure of the tracheo-bronchial tree
chapter 12|1 pages
Vaginal and Interuterine Drug Delivery
ANATOMY AND PHYSIOLOGY Mucosa Blood and nerve supply Uterine and vaginal fluid
