ABSTRACT

Prion-related diseases, known as transmissible spongiform encephalopathies (TSEs), are infectious, fatal neurodegenerative disorders for which there is no cure, treatment, nor even a means for early diagnosis. The horrific advent of Mad Cow Disease -- transmitted to humans through eating meat from steers sickened by bovine spongiform encephalopathy

chapter 6|10 pages

From the mouth to the brain

chapter 7|12 pages

Neurodegeneration in prion diseases

chapter 8|18 pages

The diagnosis problem and current tests

chapter 9|12 pages

Therapeutic approaches

chapter 11|18 pages

Other diseases of protein misfolding

chapter 12|16 pages

Prions: a common phenomenon in biology?