ABSTRACT

Plants, marine organisms, and microorganisms have evolved complex chemical defense and signaling systems that are designed to protect them from predators and provide other biological benefits. These organisms thus produce substances containing novel chemotypes that may have beneficial effects for humans. As collection methods improve and new screen

chapter 1|4 pages

Introduction

chapter 2|18 pages

Camptothecin and Its Analogs

chapter 4|24 pages

Homoharringtonine and Related Compounds

chapter 5|18 pages

Podophyllotoxins and Analogs

chapter 6|34 pages

Taxol and Its Analogs

chapter 7|14 pages

The Vinca Alkaloids

chapter 8|14 pages

The Bryostatins

chapter 15|18 pages

The Actinomycins

chapter 16|22 pages

Anthracyclines

chapter 17|18 pages

Ansamitocins (Maytansinoids)

chapter 18|18 pages

Benzoquinone Ansamycins

chapter 19|26 pages

Bleomycin Group Antitumor Agents

chapter 22|24 pages

Enediynes

chapter 23|24 pages

The Mitomycins