ABSTRACT

This reference discusses in detail the broad realm of preclinical drug development. Topics range from assessment of pharmacology and toxicology through the regulatory expectations that support clinical trials. Providing chapters on pharmacokinetics, modeling and simulation, formulation and routes of administration, toxicity evaluations, the assessm

chapter 2|56 pages

Overview

chapter 3|32 pages

Introduction

chapter 5|40 pages

Introduction

chapter 6|22 pages

Introduction

chapter 8|52 pages

Introduction

chapter 9|46 pages

Introduction

chapter 10|66 pages

Chapter Overview

chapter 11|116 pages

Introduction

chapter 12|20 pages

Introduction